A historical overview of industrial fermentation process – traditional and modern biotechnology. A brief survey of organisms, processes, products relating to modern biotechnology. Process flow sheeting – block diagrams, pictorial representation.
PRODUCTION OF PRIMARY METABOLITES
A brief outline of processes for the production of some commercially important organic acids (e.g. citric acid, lactic acid, acetic acid etc.,); amino acids (glutamic acid, phenyalanine, aspartic acid etc.,) and alcohols (ethanol, butanol etc.,)
PRODUCTION OF SECONDARY METABOLITES
Study of production processes for various classes of secondary metabolites: antibiotics: beta-lactams (penicillin, cephalosporin etc.), aminoglycosides (streptomycin etc.,) macrolides (erythromycin), vitamins and steroids.
PRODUCTION OF ENZYMES AND OTHER BIOPRODUCTS
Production of industrial enzymes such as proteases, amylases, lipases, cellulases etc., Production of biopesticides, biofertilisers, biopreservatives (Nisin), cheese, biopolymers (xanthan gum, PHB etc.,), single cell protein.
PRODUCTION MODERN BIOTECHNOLOGY PRODUCTS
Production of recombinant proteins having therapeutic and diagnostic applications, production of vaccines. Production of monoclonal antibodies. Products of plant and animal cell culture
REFERENCE
Text Books
1. Casida Jr, L.E., “Industrial Microbiology”, New Age International (P) Ltd.
2. Presscott, Dunn, “Industrial Microbiology”, Agrobios (India).
Reference Books
1. Wulf Cruger and Anneliese Crueger, “Biotechnology: A Textbook of Industrial Microbiology”, Panima Publishing Corporation.
2. Murrey Moo & Young, “Comprehensive Biotechnology”, Pergamon