Functions of Proteins, Enzymes, introduction to biocatalysts, metabolic pathways, primary and secondary metabolites
INTERMEDIARY METABOLISM AND REGULATION
Glycolysis, TCA cycle, gluconeogenesis, pentose phosphate shunt, glyoxalate shunt, fatty acid synthesis and oxidation, reactions of amino acids, deamination, transamination and decarboxylation, urea cycle, interconnection of pathways and metabolic regulation. Case study on overproduction of glutamic acid, threonine , lysine, methionine, isoleucine and ethanol.
BIOENERGETICS
High energy compounds, electronegative potential of compounds, respiratory chain, ATP cycle, calculation of ATP yield during oxidation of glucose and fatty acids.
REFERENCE
Text Books
1. Nelson, D.L. and M.M. Cox, “Lehninger’s Principles of Biochemsitry”, 4th Edition, W.H. Freemen & Co., 2005.
2. Stryer, L., “Biochemsitry”, 4th Edition, W.H. Freeman & Co., 2000.
3. Voet, D. and Voet, J.G., “Biochemistry”, 3rd Edition, John Wiley & Sons Inc., 2004.
4. Murray, R.K., etal “Harper’s Biochemistry”, 23rd Edition, Prentice Hall International, 1993.