Bio-informatics |
UNIT I |
Fundamental of Biological Systems: Cell- cell organelles- Eukaryotic,
Prokaryotic cell- Cell division- Mitosis- Meiosis- Macromolecules:
Carbohydrates- Protein- Lipids- Nucleic acid- Structure of DNA and RNAVirology-
Structure of HIV- AIDS- Cancer/ Oncogenes |
UNIT II |
Fundamentals of Bioinformatics: Definition- Bioinformatics in
industrial applications- Importance of Bioinformatics- Genomics- Types of
Genomics- Proteomics- Sequence analysis- Sequence alignment- Hidden
Markov Model- Types of Alignment- BLAST- FASTA- Interpro- Cog |
UNIT III |
Biocomputing And Bioprogramming: Rasmol- Clustalw- Biological
databases- Nucleotide sequence database- Protein sequence database- EMBLDDBJ-
Genalysis- Introduction to PERL and Bio-PERL- Introduction to SQL
commands. |
UNIT IV |
Linux And Unix For Bioinformatics: Basic Unix commands- Basic
Linux commands- Web resources in Bioinformatics. |
UNIT V |
Applied Bioinformatics: Commercial Bioinformatics- Definition for
Bioinformatics company- Transcriptome- SNP’s and their applications-
Patenting and data generation from Patent literature for commercial benefits-
PR and Bioinformatics. |
Text Books |
(i) V. R.Srinivas, 2005, Bioinformatics – A modern approach, Prentice Hall of India,
New Delhi.
(ii) J Watson, Molecular Biology of the Cell. (Unit – 1)
(iii) A. Batiza, A. Finney, Schacter, Bernia Mullis, Kary B, 2005, Bioinformatics,
Genomics, Proteomics: Getting the Big Picture, Chelsea House Publications, New
York, (Unit – 2)
(iv) H. Rashidi, 2000, Bioinformatics Basics, CRC Press Ltd. (Unit - 2)
(v) Moorhouse, Michae Barry, Paul, 2004, Bioinformatics, Biocomputing and Perl: An
Introduction to Bioinformatics Computing Skills and Practice, John Wiley & Sons.
(Unit – 3)
(vi) Cynthia Gibas, Per Jambeck, 2001, Developing Bioinformatics Computer software,
O’Reilly Publications, Sebastopol, USA (Unit – 3) |
Reference Books |
(i) N. Arumugham , Cell Biology, Manjusha Publications.
(ii) Arthur M.M Lesk 2002, Introduction to Bioinformatics, Oxford University.
(iii) Dan E.Krane, Michael L Raymer, Elaine Nicpon, Marieb 2002, Introduction to
Bioinformatics.
(iv) James Tisdal, 2001, Beginning Perl for Bioinformatics, O’Reilly Publications
Sebastopol, USA.
(v) Werner Kalowurs a.Meyer Rachael Tyndale 2001, Pharmacogenomics.
(vi) Lengauer, Thomas, 2003, Bioinformatics: From Genes to Drugs: John Wiley &
Sons Publications.
(vii) Mount David W, 2004, Bioinformatics: Sequence & Genome Analysis, 2nd
Edition, Coldspring Harbor Laboratory Press.
(viii) S.B Primrose & R.M Twyman,2002, Principles of Genome Analysis and
Genomics, 3rd Edition, Blackwell Publications. |
Websites, E-learning materials |
(i) http://www.bioinformaticsonline.org/ch/cho1/index.html |
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